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CSIRO is developing hairpin RNAi interference technology.

Licensing RNAi gene technology

Having developed the 'hairpin RNAi' gene silencing technology, CSIRO is now working with commercial partners to develop specific product applications.

  • 25 July 2005 | Updated 24 June 2014


CSIRO scientists have led the way in the development of what has been hailed as a major breakthrough in molecular biology: switching-off genes by RNA interference (RNAi).  

The technology has potential for influencing traits in plants and animals by 'switching off' an organism's genes.

The first application of this process has seen the 'vaccination' of crops against viruses in much the same way as humans are protected from diseases like measles.

More about Gene technology: gene silencing.

Product applications

CSIRO is working in partnership with commercial and academic collaborators to develop specific applications for hairpin RNAi. 

CSIRO is working in partnership to develop specific applications for hairpin RNAi.

Selected product applications include:

  • enhancing the production of biopharmaceuticals
  • driving commercial trait development in plants and animals
  • developing potent therapeutics
  • developing disease resistance in plants and animals
  • developing novel transgenic animal models
  • facilitating directed breeding and diagnostics development
  • researching whole-genome and functional genomics.

In parallel, our scientists continue to innovate to develop new tools, technologies and techniques to improve the delivery, potency and ease of use of our hairpin RNAi technologies.

Licensing opportunity

In order to provide access to this powerful technology to a wide range of market sectors, CSIRO has embarked on a broad licensing strategy. 

Licence rights are available in selected fields to organisations interested in undertaking R&D or wishing to develop, market and sell products incorporating hairpin RNAi.

Current licensees to CSIRO hairpin RNAi IP rights include:

  • Benitec Ltd (hairpin RNAi for human therapeutic uses & research)
  • Merck & Co (human health research)
  • Promega (research tools)
  • Bayer CropScience (selected crops)
  • Florigene & Suntory Flowers (ornamental flowers)
  • genOway (genetically modified mice for R&D)
  • Artemis Pharmaceuticals (genetically modified mice)
  • Revivicor (pig health & pig organs for transplantation).

Find out more about Hairpin RNAi.