Understanding and harnessing stem cells

We’re harnessing the unique biological properties of stem cells, to help develop new drugs and reagents for stem cell characterisation and stem cell-based therapies.

The Challenge

Using stem cells to treat disease

It is becoming evident that more and more human diseases, particularly degenerative diseases, might be treatable with stem-cell based therapies.

However in order for cell-based therapies to be successful, it is important for scientists to be able to manipulate stem cells so that they have the required characteristics for successful transplantation.

We are developing technology to generate larger quantities of safe, functional stem cells.

More specifically, scientists must be able to control the cells so that they:

  • proliferate without loss of phenotype
  • differentiate into the required cell types
  • survive transplantation and home to the required tissue
  • integrate into the surrounding tissue
  • function correctly in the patient
  • avoid harm to the patient.

Our Response

Improving understanding and safety

We’re researching the basic biology of stem cells, and developing new technologies for controlling their growth and development. This will help with the development of new drugs and reagents for stem cell characterisation and stem cell-based therapies.

Working with national and international colleagues, we are also developing technology to generate larger quantities of safe, functional stem cells. This includes developing new reagents for characterising cells and innovative techniques for growing cells on smart biomaterials.

Case studies

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