Taking advantage of proteins

Our research reveals the roles of proteins in molecular and cellular biology and how they can be used to treat diseases.

The Challenge

Taking advantage of proteins in product development

Proteins are nature’s workers. Their recipes are written in DNA and their functions span forming structures like muscles, carrying out chemical reactions, fighting infections, acting as chemical messengers and transporting smaller molecules.

Understanding and making use of proteins has many benefits, from cleaning up pesticides to designing drugs to treat infectious diseases.

Our Response

Building a better picture of proteins

We research the structure, function and biochemical significance of proteins. We unravel their roles in molecular and cellular biology, how they are regulated and how they work.

Crystal structure of AtzF, an enzyme that looks a little like a map of Australia. AtzF is one of six enzymes in the degradation pathway of the herbicide Atrazine. We're working towards using the enzymes to clean up the environment, a process called bioremediation.

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Our expertise spans:

  • molecular and cellular biology – manipulating DNA to produce proteins
  • protein and antibody engineering – designing proteins and antibodies for applications in human health and environmental management
  • protein purification – producing proteins for applications like crystallography, to reveal protein structure
  • fermentation – engineering bacteria such as E. coli to manufacture large quantities of proteins for research or large-scale production.

Case study

  • Cinder - Tinder for protein crystallography

    We’ve used mobile technology coupled with crowd-souring to allow people to “score” protein crystallisation images. As more people score we get a better training set to help our machine algorithms learn how to score for us.

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