Coronary
disease is one of Australia's biggest killers. And despite all the
best medical attention in the world... if heart arteries are badly
blocked... they have to be replaced.
Up till now
the patients own body has provided the spare parts with arteries
from limbs being used... but soon this may not be necessary.
It's usually
a build-up of cholesterol and fatty deposits that causes cardiac
disease. And if peripheral vascular disease has set in, taking an
artery from a patient's limb, will not always be possible.
Scientists
from CSIRO and Bionova are creating an artificial artery for use
in the human body. It is a composite of natural collagen and synthetic
polymer mesh. The mesh acts as a reinforcement for the natural collagen
so that this replacement artery has the strength and durability
required for the demanding job of keeping a heart pumping. But the
body has a natural disposition to reject anything foreign.
Fortunately
for humans the natural collagen that sheep manufacture is compatible
with the human body. So the lengths of mesh are placed just under
the sheep's skin for it to become coated with the animals collagen.
This bio synthetic
composite material is further processed by Bionova so that it becomes
compatible with human tissue and cells.
"Over the
last 10 years, extensive testing of a variety of physical and mechanical
properties in the laboratory and clinical studies, has enabled the
development of a vessel that closely matches the natural elasticity
of a blood vessel."
This technique
has already been used successfully in operations on damaged limb
arteries, and scientists hope that soon it will also be a life saver
in cardiac surgery.
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