Our researchers are developing and evaluating new platform materials and devices for applications in tissue repair, replacement and regeneration.
Our capabilities
The aim of our biomaterials and regenerative medicine research is the development and evaluation of new platform materials and devices for applications in tissue repair, replacement and regeneration.
These innovative technologies will impact positively on the health outcomes of an ageing Australian society, improving both quality of life and offsetting the rate of progression to more expensive forms of healthcare.
We have three major research priorities:
Bioactive scaffolds and adhesives
To design, synthesise and apply novel materials for application in tissue repair or regeneration.
Peripheral nerve repair and infection control
In conjunction with our partners at Bionic Technologies Australia [external link] to develop innovative methods for the treatment of nerve damage and to minimize the risk of infection following biomaterial implantation.
Photo-crosslinking
To further develop a CSIRO invented photoactive oxidative cross-linking technology using a number of well-defined matrix substrates for tissue sealant (PhotoSeal™). CSIRO is seeking partners to exploit our tissue sealant (PhotoSeal™) and tissue engineering applications.
Biomedical adhesives
To develop high strength, biodegradable surgical adhesives with novel cure mechanisms.
Collagen scaffolds
CSIRO has several projects developing new collagen-based materials with commercial partners. CSIRO also provides consultancy on collagen and extra-cellular matrix proteins.
Tissue Engineering
To develop methods, for example in cartilage repair, using rapid culturing methods to expand and control cell behaviour, in combination with novel polymer delivery scaffolds.
Biomanufacturing
To develop new platform technologies of smart polymer surfaces that control cell function and fate.
Stem cells
In collaboration with our partners in Corporate Research Centre for Polymers (CRC Polymers) [external link] (Australian Stem Cell Centre, Monash University, and Swinburne University), we are developing novel surfaces for the proliferation and differentiation of adult (haemopoeitic) and embryonic stem cells.
Bioactive Surfaces
This research seeks to develop platform technologies capable of controlling biological response for application in cell arrays, microfluidic technologies, antibacterial coatings and bioreactors. CSIRO is seeking partners to exploit provisional IP.
Ophthalmic Biomaterials
To develop, in collaboration with our partners in Vision Correction Research Centre (Vision CRC) [external link], novel ophthalmic products:
Dynamic Vision
An accommodating intraocular lens which restores the ability of the eye to focus at a range of distances, thus curing presbyopia.
Corneal Inlay/Onlay
A corneal inlay/onlay that will enable safe, permanent, but reversible, refractive correction at lower cost and lower risk than current surgical technologies such as laser surgery. Corneal inlay is in a phase 1 clinical trial.
Vision CRC are seeking partners to take these products to market.
Research highlights
New companies:
New products:
New opportunities:
Our biomaterials and regenerative materials customers:
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Aortech Biomaterials Pty Ltd
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PolyNovo Biomaterials Pty Ltd
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Vision CRC Ltd
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CRC Polymers
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Bionic Technologies Australia
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CollTech
CSIRO also provides consultancy and contract analytical/biocompatibility services to a wide range of clients such as Colltech (collagen processing).
Read about CSIRO's work in Treatment.
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