CSIRO helped Australian medical device company Admedus to investigate further opportunities for their CardioCel product.

The challenge

Exploring stem cells for cardiovascular treatment

Admedus is an Australian small to medium-sized enterprise that invests in next generation technologies for the healthcare sector. They look to research and development to continue to improve their product and service offerings.

Admedus saw an opportunity to grow their CardioCel product (a type of cardiovascular scaffold) into other emerging applications.

Our response

A superior platform for stem cell growth

CSIRO’s researchers joined Admedus to explore the suitability of CardioCel for use in stem cell therapy in heart failure patients by comparing it with another commonly-used product. They found that CardioCel was well suited to cardiovascular cell therapy and might have applications in other areas of stem cell delivery too.

The results

A new pulse for heart health

  • This research identified a new set of potential business opportunities for Admedus’ existing product CardioCel.
  • Chief Scientific Officer, David Rhodes, said, “Through combining [our] expertise with that of CSIRO, we see the potential for additional projects with CSIRO down the track. There are other techniques we would like to explore."
  • “The results have shown that CardioCel enhances the ability for tissues to repair and that it is well-suited for cardiovascular cell therapy,” said CSIRO’s Dr Werkmeister.
  • The results showed that the company’s novel engineering process used to prepare CardioCel provides a superior tissue platform for growing stem cells.
  • “There is the potential to use our material in other areas of stem cell delivery as well, for example it might help speed the recovery when used in the repair of knee joints or in the rebuilding of vessels,” said Dr Rhodes. “While this still needs further research, these results are promising and we have the grounds for exploring it further.”

This project was supported by the Enterprise Connect Researchers in Business program, which was an Australian Government initiative which provided funding to support the placement of researchers directly into businesses to help them develop and implement new commercial ideas.

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