We are looking for healthy individuals living in Adelaide to participate in a study to determine whether specific molecular changes in saliva, cheek cells and blood samples could be used for early diagnosis of Alzheimer’s disease risk in humans.

Background

More than 200 people are diagnosed with Alzheimer's disease in Australia every day. Alzheimer's disease not only affects the quality of life, health and wellbeing of those affected but also leads to a significant financial burden at an individual level as well as for our wider community. However, to date, there is no conclusive diagnostic test available. It is important, therefore, to try and identify potential early biomarkers that may help us to design preventative measures.

About this study

To accurately assess changes in people with neurodegenerative disease, we need a group of healthy age and gender-matched volunteers (normal controls) to compare results. We are currently seeking volunteers and would greatly appreciate your contribution as a control volunteer to attend the CSIRO Clinic at SAHMRI on North Terrace, Adelaide for a single 45 minute visit.

The clinic visit will involve:

  • a non-fasted blood sample will be collected by trained and experienced staff
  • a cheek cell sample will be collected using a small toothbrush that will be rotated against the inside of the cheeks
  • a saliva sample will be collected by drooling in a tube
  • completion of a questionnaire plus a 'mini mental state examination' (MMSE)
  • no dietary or pharmacological treatment or intervention is involved
  • on completion of the study, participants will receive a Coles/Myer gift card valued at $50 to acknowledge their valuable contribution to scientific research.

Study criteria

You will need to meet the following criteria to participate in this study:

  • are healthy and aged 55 years and above
  • not clinically diagnosed with Mild Cognitive Impairment, Alzheimer's disease or Parkinson's disease
  • no family history of Mild Cognitive Impairment, Alzheimer's disease or Parkinson's disease
  • not undergoing chemotherapy/radiation treatment for cancer
  • not supplementing your diet with the vitamins Vitamin B12, folate and vitamin D.

Participate in this study

If you would like to participate, please register your interest by completing the online registration form.

If you have any queries about the SAND study please call Dr Wayne Leifert on 8303 8821 or email CRUstudies@csiro.au.

This study has been approved by the CSIRO Health and Medical Research Human Research Ethics Committee.

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