We’re harnessing the unique biological properties of stem cells, to help develop new drugs and reagents for stem cell characterisation and stem cell-based therapies.
Using stem cells to treat disease
It is becoming evident that more and more human diseases, particularly degenerative diseases, might be treatable with stem-cell based therapies.
However in order for cell-based therapies to be successful, it is important for scientists to be able to manipulate stem cells so that they have the required characteristics for successful transplantation.
More specifically, scientists must be able to control the cells so that they:
- proliferate without loss of phenotype
- differentiate into the required cell types
- survive transplantation and home to the required tissue
- integrate into the surrounding tissue
- function correctly in the patient
- avoid harm to the patient.
Improving understanding and safety
We’re researching the basic biology of stem cells, and developing new technologies for controlling their growth and development. This will help with the development of new drugs and reagents for stem cell characterisation and stem cell-based therapies.
Working with national and international colleagues, we are also developing technology to generate larger quantities of safe, functional stem cells. This includes developing new reagents for characterising cells and innovative techniques for growing cells on smart biomaterials.
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