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Our capabilities include:

  • stem cell biology, virology and immunology.
  • protein production, structural biology and biophysical, biochemical and cell biology assays.
  • screening libraries, synthetic organic and medicinal chemistry, drug delivery and process development.

We work across a range of therapeutic areas including oncology, infectious disease, autoimmune conditions, vascular disease, ocular disease, parasitic infections and pain.

Support for SMEs

CSIRO offers start-ups and SMEs opportunities to initiate and faciliate their R&D programs through access to our world-class facilities and researchers. We also offer matched funding support and training and can help you navigate the research ecosystem.

Case study: Cancer Therapeutics CRC(CTx)

Over 13 years through the Cancer Therapeutics Cooperative Research Centre (CRC), CSIRO contributed to development of globally recognised Australian small molecule anticancer drug discovery projects, resulting in:

  • new anticancer drugs in clinical trials.
  • start-up of new Australian biotech companies.
  • financial returns from licensing deals which continue to support Australia’s drug discovery industry.

The CRC brought together biology target expertise and drug discovery capabilities from leading medical research institutes and universities together with commercial acumen from industry. CSIRO provided capabilities in protein production, biophysics as well as the structural biology that underpinned much of the IP developed between 2014 and 2020.

CSIRO continues to work with companies aiming to find cures for cancer.

Working with us – Our capabilities in small molecule drug discovery and development

  • Target identification
  • in vivo target biology and validation
  • in vitro target biology & validation
  • construct design
  • Process development & scale up
  • Wildtype (wt) & knockout (ko) cell lines
  • Protein expression & purification
  • SPR/biophysics development & testing
  • Biochemical assay development & testing
  • Bespoke cell assay development & testing efficacy cytotoxicity target engagement oncology immunology immuno-oncology psychoactives anti-microbials anti-inflammatories
  • Compound & fragment libraries
  • High-throughput screen support & tech transfer
  • in vivo testing efficacy safety target specifity animal models
  • Bioconjugation theranostics drug conjugates
  • Structural biology / modelling
  • Med chem support/design, synthesis optimisation, analysis/characterisation formulation, compound logistics
  • Market analysis, business development & commercialisation
Our capabilities in small molecule drug discovery and development

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Work with us

We partner with small and large companies, government and industry in Australia and around the world. Explore how our science and technology can help your organisation.

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